Number of COVID-19 cases required in a population to detect SARS-CoV-2 RNA in wastewater in the province of Alberta, Canada: Sensitivity assessmentResearch article Published on 2023-03-012022-10-05 Journal: Journal of environmental sciences (China) [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] analysis Analysis collected Community COVID-19 COVID-19 case COVID-19 cases Critical dataset defined detect detection rate Detection sensitivity Epidemiology Estimated IMPROVE input median negative test number plant positive prevalence of COVID-19 Probability Probit analysis provided required RT-qPCR SARS-CoV-2 SARS-CoV-2 RNA SARS-CoV-2 RNA detection sensitivity study period Support Surveillance threshold Treatment unique wastewater [DOI] 10.1016/j.jes.2022.04.047 [Article Type] Research article
Integrated COVID-19 Predictor: Differential expression analysis to reveal potential biomarkers and prediction of coronavirus using RNA-Seq profile data통합 COVID-19 예측자: RNA-Seq 프로필 데이터를 사용하여 잠재적인 바이오마커 및 코로나바이러스 예측을 밝히기 위한 차등 발현 분석Article Published on 2022-08-012022-09-11 Journal: Computers in biology and medicine [Category] COVID19(2023년), MERS, SARS, 바이오마커, 변종, [키워드] Accuracy adjusted Analysis applied association bioinformatics Biomarker classification Classifier collected Consensus Control coronavirus COVID-19 COVID-19 cases COVID-19 pandemic DEGs DESeq2 Differential expression analysis differentially expressed gene Differentially expressed genes disease transmission down-regulated genes experiment experimental analysis expressed feature filtered gene count Genome healthy identify input intersection and union issue Limma machine machine learning machine learning model machine learning models matter moderate P-value pandemic performed Potential biomarker potential biomarkers predict prediction predictor processed RNA-Seq SARS-CoV-2 SARS-CoV-2 virus SARS-CoV-2. sequence significantly Spread statistical SVM the SARS-CoV-2 virus trend up-regulated viral disease Virology [DOI] 10.1016/j.compbiomed.2022.105684 PMC 바로가기 [Article Type] Article
Epigenetic mechanisms regulate sex-specific bias in disease manifestations후성 유전적 메커니즘은 질병 발현에서 성별에 따른 편향을 조절합니다Review Published on 2022-08-012022-09-11 Journal: Journal of Molecular Medicine (Berlin, Germany) [Category] 유전자 메커니즘, [키워드] affecting Anatomy Autoimmune disorders Cancer change chromosome Clinical outcome clinical study COVID-19 COVID-19 infection differential expression disease disease manifestation disease onset Diseases Effect Epigenetic epigenetic modification epigenetics exhibit explained expression fibrosis Genes Genetic Genetic and epigenetic changes Hormones immune response immune responses immune system implicated inactivation infections input involved Liver fibrosis mechanism Neuropsychiatric Neuropsychiatric diseases progression recent regulate Respiratory disease respiratory diseases response to therapy responsible Sex Sex bias Sex chromosome sex hormone Sex hormones susceptibility therapeutic targets therapy underlying disease X chromosome X-inactivation X-linked X-linked gene X-linked genes. [DOI] 10.1007/s00109-022-02227-x PMC 바로가기 [Article Type] Review
Automated detection of COVID-19 cases from chest X-ray images using deep neural network and XGBoost심층 신경망 및 XGBoost를 사용하여 흉부 X선 이미지에서 코로나19 사례 자동 감지Article Published on 2022-08-012022-09-11 Journal: Radiography (London, England : 1995) [Category] SARS, 치료기술, [키워드] Accuracy Activation Algorithm approach approaches assist can be used Chest chest X-ray Chest X-ray image Chest X-ray images chests coronavirus disease COVID-19 COVID-19 case COVID-19 cases COVID-19 diagnosis COVID-19 pandemic deep Deep neural network (DNN) DenseNet169 detect diagnosing evaluate experiment faster feature Gradient heatmap implementation initial input network Neural patients with COVID-19 people with COVID-19 problems radiologist Radiologists researcher sensitivity specificity the disease the patient was used X-ray XGBoost. [DOI] 10.1016/j.radi.2022.03.011 PMC 바로가기 [Article Type] Article
A radiomics-boosted deep-learning model for COVID-19 and non-COVID-19 pneumonia classification using chest x-ray images흉부 엑스레이 이미지를 사용하여 COVID-19 및 비-COVID-19 폐렴 분류를 위한 방사성 부스트 딥 러닝 모델Article Published on 2022-05-012022-09-11 Journal: Medical physics [Category] COVID19(2023년), SARS, 치료기술, [키워드] Accuracy Analysis approach assigned AUC Chest chest X-ray Chest X-ray images COVID-19 COVID-19 pandemic deep learning demonstrated develop evaluated feature healthy highest implementation Inclusion input investigated network architecture Non-COVID-19 Pneumonia Radiomics random assignment reduced reduction robustness ROC ROC AUC ROC Curve ROC curves selected sensitivity specificity suggested Variation X-ray X-ray. [DOI] 10.1002/mp.15582 PMC 바로가기 [Article Type] Article
Prediction Model of Adverse Effects on Liver Functions of COVID-19 ICU PatientsCOVID-19 ICU 환자의 간 기능에 대한 부작용 예측 모델Article Published on 2022-04-252022-09-11 Journal: Journal of Healthcare Engineering [Category] COVID19(2023년), SARS, 치료기술, [키워드] Adverse age ANN assist caused Classifier classifiers collected data country COVID-19 Decision tree develop disease Effect feature function global health Health ICU ICU Patients Illness severity Infection input Laboratory testing liver Liver damage liver diseases liver failure lockdowns machine machine learning machine learning algorithm Machine learning algorithms medical staff Model Naïve Bayes Organ failure outcome patient data patients performed predict prediction Predictive model predictive models risk SARS-CoV-2 severe disease social distancing susceptible SVM tested Topic Treatment variable virus [DOI] 10.1155/2022/4584965 PMC 바로가기 [Article Type] Article
Computational prediction of potential inhibitors for SARS-COV-2 main protease based on machine learning, docking, MM-PBSA calculations, and metadynamics기계 학습, 도킹, MM-PBSA 계산 및 메타역학을 기반으로 한 SARS-COV-2 주요 프로테아제에 대한 잠재적 억제제의 컴퓨터 예측Article Published on 2022-04-222022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 신약개발, 치료기술, 치료제, [키워드] alternative ambenonium approach approved binding energy calculated CHARMM complex Compound compounds COVID-19 dataset described detect Diseases docking docking experiment drug emerging disease enrichment Factor FDA highlighting Histamine histamine receptor HIV-1 reverse transcriptase house inhibit inhibitor input Interaction knowledge lack Metadynamics Mitigation molecules MPro output PDB predict protease Protein protein targets rates of infection receptor researcher reverse transcriptase SARS-CoV-2 main protease SARS-CoV-2 Mpro scored Serotonin strong interaction the epidemic time-consuming Treatment [DOI] 10.1371/journal.pone.0267471 PMC 바로가기 [Article Type] Article
Efficient COVID-19 CT Scan Image Segmentation by Automatic Clustering Algorithm자동 클러스터링 알고리즘을 통한 효율적인 COVID-19 CT 스캔 이미지 분할Article Published on 2022-03-302022-09-11 Journal: Journal of Healthcare Engineering [Category] 변종, [키워드] Accuracy Algorithm automated Automatic carried chest CT scan class classification COVID-19 COVID-19 disease COVID-19 treatment criteria CT scan detect develop disease Efficiency efficient ENhance experiment False negative faster feature Features function help Image Image segmentation input introduced iteration iterations Local machine-learning measure Population size Precision random Random forest recall reported RT-PCR test Segmentation specificity SSA test result tested threshold value time-consuming Treatment Trial variant [DOI] 10.1155/2022/9009406 PMC 바로가기 [Article Type] Article
Importance of sample input volume for accurate SARS-CoV-2 qPCR testing정확한 SARS-CoV-2 qPCR 검사를 위한 시료 투입량의 중요성Article Published on 2022-03-222022-09-11 Journal: Analytica chimica acta [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 causative agent Concentration Consistency coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 sample Ct-value false-negative Importance Inconclusive initial input nucleic acid nucleic acid testing Occurrence outcome pandemic Poisson Poisson distribution Probability purified RNA qPCR qPCR assay qPCR test Quantitative random resulting reverse transcription PCR RNA RNA molecule robustness Sample Sample input. SARS-CoV-2 SARS-CoV-2 testing Sensitivity and specificity severe acute respiratory syndrome Coronavirus significantly Viral load Volume was used [DOI] 10.1016/j.aca.2022.339585 PMC 바로가기 [Article Type] Article
BEMD-3DCNN-based method for COVID-19 detectionBEMD-3DCNN 기반 COVID-19 탐지 방법Article Published on 2022-03-012022-09-11 Journal: Computers in biology and medicine [Category] SARS, 치료기술, [키워드] 3DCNN analyzed backbone BEMD block can not classification Context-aware attention. coronavirus COVID-19 COVID-19 virus current dataset decomposition deep learning detect detection system diagnostic effective experiment experiments followed by help include information information processing input Medical imaging mode outbreak patients pneumonia cases positive priority PROTECT Research robust selected Spread virus Wuhan Wuhan, China X-ray [DOI] 10.1016/j.compbiomed.2021.105188 PMC 바로가기 [Article Type] Article